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Capex Model

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N-Heterocycle Formation Cartridges

H001 - Morpholine

H002 - Oxazepane

H004 - 2-Methylmorpholine

H005 - Piperazine

H006 - Diazepane

H007 - 3-Methylmorpholine

H010 - Morpholine-2-spiro-(3-Pyr)

H011 - Morpholine-2-spiro-(4-Pip)

H090 - 9-OMe-Benzoxazepane

H091 - 7-Br-9-OMe-Benzoxazepane

Reductive Amination Cartridges

R001 - Reductive Amination

PROTAC Formation Cartridges

P001 - CRBN-PEG1

P002 - CRBN-PEG2

P003 - CRBN-PEG3

P004 - CRBN-PEG4

P005 - CRBN-PEG5

P001L - CRBN-PEG1

P002L - CRBN-PEG2

P003L - CRBN-PEG3

P004L - CRBN-PEG4

P005L - CRBN-PEG5

P021 - VHL-PEG1

P022 - VHL-PEG2

P023 - VHL-PEG3

P024 - VHL-PEG4

P025 - VHL-PEG5

Biotin tag cartridges

BT002 - Biotin tag-PEG2-NH2

BT003 - Biotin tag-PEG3-NH2

BT004 - Biotin tag-PEG4-NH2

BT022 - Biotin tag-PEG2-a-COOTfp

BT023 - Biotin tag-PEG3-a-COOTfp

BT024 - Biotin tag-PEG4-a-COOTfp

BT032 - Biotin tag-PEG2-COOTfp

BT033 - Biotin tag-PEG3-COOTfp

BT034 - Biotin tag-PEG4-COOTfp

Mitsunobu

M001 - Mitsunobu

Amide Formation

A011 - Amide Formation

Deoxyfluorination

F001 - Deoxyfluorination

Azide Formation

A001 - Azide Formation

Protection group chemistry

B001 - Boc protection 0.5 mmol

B002 - Boc protection 1.2 mmol

B011 - Boc deprotection

B021 - Silyl deprotection

B031 - Cbz protection

B032 - Nosyl protection

Suzuki coupling

C001 - Suzuki DPP-Pd

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